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Soy protein-An overview on testosterone levels and osteoporosis

Hopefully we all came across a ton of questions and talks on soy protein and its effects whether it is good or bad ?. Though it good, what is the recommended allowances per day? is it good for postmenopausal women? why it is not good for men to consume soy protein? and so on...

Actually coming up with right answer is difficult as everyone's physiology is unique and the right answer depends on who the asker is!
In spite of all, Today i came up with two concepts which are related to soy protein and its effects with possible mechanisms.

Post menopausal women are at risk for health problems related to estrogen deficiency such as cardiovascular diseases, osteoporosis etc.
Research has shown that  adding soy protein and isoflvones (Its a polyphenolic compound that posses both estrogen agonist and antagonist receptor (or) It is known to be estrogen analogues and bind to estrogen receptors) in the eating plan can,
  • Increase high density lipoprotein levels , 
  • Increases mononuclear cell low denstiy lipo protein receptor mRNA,
  • Intake of soy protein and isoflavones may decrease the risks asssociated with cardiovascular diseases and also it protect against spinal bone loss
The study has suggested the subjects to take 40 g of soy protein and 2.5 mg of isoflvones per gram of protein per day and this group has shown a significant differences in the above mentioned variables.

And the another big question on soy protein is why it is not good for men and what happens if?

The study on healthy male adults (18 yrs or above) says consumption of soy protein may decrease the level of serum testosterone by 19% in 28 days then serum testosterone and leutinizing hormone levels are increased within 2 weeks after they discontinued soy protein. During the study, subjects were asked to intake 56 g of soy protein powder daily for 28 days and thus decrease the serum testosterone levels and the soy protein acts as an estrogen bets agonist.

The mechanism by which soy intake may influence serum testosterone are unclear. Because soy isoflavones possess some estrogen activities. so that, soy may exert an effect on of the hypothalamic-pituitary gonadal axis to down regulate the estrogen and androgen synthesis.

An another possible mechanism for the results, maybe the inhibition of enzymes involved in hormone metabolismby phytoestrogens such as soy, including 17-Beta hydroxysteroid dehydrogenase and 5-alpha reductase which could ultimately lead to lower the levels of testosterone.

 

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